NAC (N-acetyl-cysteine) , derivative of the amino acid L-cysteine, assisst in healthy antioxidant and
detoxification mechanisms in the body.
NAC supports antioxidant activity by neutralizing hydrogen peroxide, hypochlorous acid, and hydroxyl
radical and also serves as a source of sulfhydryl groups. In addition, NAC enhances production of the
glutathione—a key component of both antioxidant and detoxification enzymes.
NAC is known for its support of normal mucous production and may positively assisst in respiratory
function and eye health, especially when consumed over a prolonged period.
NAC may protect cell and tissue health by supporting normal metal status in the body.
NAC may significantly increase circulating levels of glutathione in the body, which is then incorporated
into antioxidant and detoxification enzymes/ glutathione peroxidase,glutathione reductase, Glutathione S –
transferase./ Through the activity of these enzymes, glutathione directly supports antioxidant activity,
phase II detoxification, breakdown of metabolites, toxicants , and other compounds in the body.
A variety of factors may determine glutathione requirements, including level of exposure to toxins/
pollutants , increased phase I detoxification activity, and overall need for antioxidant support. Maintaining
glutathione levels may be important to maintaining the health of the immune systems, respiratory system
and hepatic functions, as well as supporting antioxidant protection of lipids and proteins and supporting
the normal response to inflammation
NAC helps immune system to fight viruses, microbes . Research showed, in vitro study,
that “ after influenza virus and RSV / Respiratory Syncytial Virus / infection there is an increase in
intracellular levels of H2O2 /oxidants and a decrease in intracellular thiols. NAC restored this
imbalance by decreasing the H2O2 concentration and restoring thiol levels. As a consequence , virus
titers decreased and viral proliferation was inhibited. “
NAC may restore epithelial functions after RSV/ respiratory syncytial virus / infection via inhibition of the
expression of adhesion molecule and RSV replication , and by restoring antioxidant capacity, intracellular
H202 levels and glutathione content in normal human bronchial epithelial cells/ PubMed 23118923