We have empowered traditional Berberine into a powerful herbal trio, designed to support a healthy glucose and lipid metabolism.
Our enhanced Berberine formula consists of the following ingredients:
Coptis chinensis rhizoma – (10% Berberine) 500 mg
Auklandia lappa root – 100 mg
Glycyrrhiza glabra – Licorice (20% Glycyrrhizic acid) 50 mg
These have all been used extensively in Traditional Chinese Medicine for their anti-bacterial or beneficial gastrointestinal properties.
Coptis chinensis has been used since long in TCM as an anti-bacterial herb. Furthermore, it is known to being beneficial in assisting the maintenance of healthy blood glucose and lipid levels as well as decreasing insulin resistance.
Studies have shown that Berberine has helped maintained a healthy liver in patients diagnosed with Non-Alcoholic Fatty Liver by reducing triglycerides, LDL cholesterol, liver enzymes and hepatic fat content.
Berberine is also known for its ability to help maintaining a healthy condition within the brain tissue (it has even been reported to decrease amyloid formation).
Root extract from Auklandia lappa – Saussurea costus, a South Asian thistle – is a common remedy in TCM against gastrointestinal problems and obesity. Pharmacological studies conducted in China, Korea and Japan showed that the active constituents may have anti-ulcer, anti-carcinogen, anti-inflammatory, anti-mycobacterial and vast-relaxant properties.
Commonly known as liquorice, Glycyrrhiza glabara is one of the most commonly used herbs in TCM. It has been used to treat many ailments, such as shortness of breath, cough, wheezing, fatigue, weakness, loose stool, diarrhoea, arrhythmia and muscle spasms to name a few.
Recent studies have confirmed Liquorice’s positive effect on the health of the lipid metabolism and insulin resistance through Glycurrhizin, one of it’s major constituents.
Sources & References
1.Yin J, Huili Xing, Jianping Ye, Efﬁcacy of Berberine in Patients with Type 2 Diabetes in study A! “Berberine signiﬁcantly decreased Hb A1C levels in diabetic patients who took 500mg 3 times daily for 13 weeks from 9.5% to 7.5% and the effect of decreasing HbA1C was comparable with metformin” in study B , Hb A1C was reduced from 8.1 to 7.3 , fasting plasma insulin and HOMA -IR were reduced by 28.1% and 44.7% respectively”
2.Zhang Y, Zou D, Liu W, Yang J et allTreatment of type 2 Diabetes and Dyslipidemia with the natural plant alkaloid berberine PMID 18397984 “randomized, double blind placebo-controlled and multi-center trial showed that treatment with berberine 0.5 g twice a day for 3 months in 57 diabetic patients signiﬁcantly reduced levels of fasting and postprandial plasma glucose and Hb A 1C 1.4 and 3.1 nmol/ L and 0.9% respectively, which was accompanied with decreasing triglycerides and total cholesterol concentration by 35.9% and 18% respectively”
3 .Hong -Mei Yan Ming-Feng Xia and all Efﬁcacy of Berberine in Patients with Nonalcoholic Fatty Liver Disease “after treatment hepatic fat content /HFC/ decreased by 57.2% in the LSI / Life Style Intervention/ plus berberine , and by 36.4% in the LSI group. Treatment with LSI plus berberine! caused more reduction of HFC as compared to LSI alone.Moreover the effect of berberine on HCF was no smaller than that of PGZ 15mg/ day . Liver enzymes were also reduced in all groups after treatment…
4. Sun R1, Yang N1, Kong B2, Cao B3, Feng D1, Yu X1, Ge C1, Huang J1, Shen J2, Wang P1, Feng S1, Fei F1, Guo J1, He J1, Aa N1, Chen Q2, Pan Y2, Schumacher JD2, Yang CS2, Guo GL2, Aa J4, Wang G1 “Orally administered berberine modulates hepatic lipid metabolism by altering microbial bile acid metabolism and the intestinal FXR signaling pathway. . 5.Berberine increases adipose triglyceride lipase in 3T3-L1 adipocytes through the AMPK pathway”.
5.Isolation of Betulinic Acid, its Methyl Ester and Guaiane Sesquiterpenes with Protein Tyrosine Phosphatase1B inhibitory activity from the Root of Saussurea Lappa . C.B.Clark. Ji Yuong Choi, Min Kuyn Na, Seung Ho Lee, Eun Young Boe, Bo Yeon Kim, and Jong Seog Ahn. College of Pharmacy Youngnam University, Gyueongsan, Gyuengbuk 712-749 Korea.
6.Korea Research Institute of Bioscience and Biotechnology (KRIBB), 52 Eoun-dong, Useung-gu, Daejon 305-806, Korea 6.Chen J.K, Chen TT Medical Herbology and Pharmacology City of Industry , CA Art of medicine Press 2004 p. 493-494
7.Glycerrhizin ameliorates insulin resistance, hyperglycemia, dislipidemia and oxidative stress in fructose induced Metabolic Syndrome-X in Rat Model. Deparment of Biophysics, Molecular Biology and Bioinformatics, University College of Science, University of Calcutla, 92 Acharyya Prafulla Chambra Road, Kolkata 700 009, India